FeedbackIn settings with high TB transmission, adults and adolescents living with HIV who have an
unknown or a positive LTBI test and are unlikely to have active TB disease should receive at least
36 months of daily isoniazid preventive treatment (IPT). Daily IPT for 36 months should be given
whether or not the person is on ART, and irrespective of the degree of immunosuppression,
history of previous TB treatment and pregnancy, in settings considered to have a high TB
transmission as defined by national authorities.
Guideline Citation
WHO consolidated guidelines on tuberculosis: tuberculosis preventive treatment. Geneva: World Health Organization;
2020. Licence: CC BY-NC-SA 3.0 IGO.
2020. Licence: CC BY-NC-SA 3.0 IGO.
Grade Certainty of evidence
Grade Strength
Grade Certainty of evidence label
Recommendation Direction