Operational Handbooks

3.3 Algorithms for informing the decision to treat TB infection or TB disease among people living with HIV

For people living with HIV, screening and diagnostic algorithms should serve both to include TB disease to identify those requiring treatment and to exclude TB disease to determine eligibility for TPT. Lack of access to any of the tools described here should not be a barrier to TB screening or ruling out TB to allow initiation of TPT. Here we present five practical algorithms that combine WHO-recommended TB screening tools (W4SS, CRP, CXR and mWRD) with diagnostic tools (LF-LAM and mWRD) for people living with HIV.