Operational Handbooks

1.1 Background

Globally, tuberculosis (TB) continues to be a significant public health problem. It has been estimated that about a quarter of the world’s population was infected with Mycobacterium tuberculosis (Mtb) bacteria (1). In 2023, an estimated 10.8 million infected individuals went on to develop TB disease, while 8.2 million were diagnosed and reported to the World Health Organization (WHO) (2).

Acknowledgements

The update of this operational handbook on tuberculosis (TB) was led by Nazir Ahmed Ismail, Patricia Hall-Eidson, Carl-Michael Nathanson and Alexei Korobitsyn, with support from Cecily Miller, Dennis Falzon, Avinash Kanchar and Matteo Zignol, under the overall direction of Tereza Kasaeva, Director of the World Health Organization Global Programme on Tuberculosis & Lung Health (WHO/GTB).