FeedbackThe recommendations and remarks in this policy guideline on tuberculosis (TB) are the result of the collaborative effort of professionals from a range of specialties. The World Health Organization (WHO) is grateful for their time and support. There were separate Guideline Development Groups (GDGs) for each of the guidelines that have been included in these consolidated guidelines. The acknowledgements provided immediately below are specific to WHO guidelines that are new in this edition. Acknowledgements for prior guidelines are summarized in Web Annex A.
The production and writing of this document – WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis – was coordinated by Alexei Korobitsyn and Patricia Hall-Eidson, with the support of Carl-Michael Nathanson, under the guidance of Matteo Zignol and the overall direction of Tereza Kasaeva, Director of the WHO Global Programme on Tuberculosis & Lung Health (WHO/GTB).
Low complexity nucleic acid amplification testing for detection of TB and resistance to rifampicin
Concurrent testing
WHO steering committee
The preparation of this section of the guidelines was overseen by Alexei Korobitsyn with input from Annabel Baddeley, Annemieke Brands, Dennis Falzon, Tereza Kasaeva, Cecily Miller, Carl-Michael Nathanson, Jasmine Solangon, Maria de los Angeles Vargas, Sabine Vercuijl, Kerri Viney, and Matteo Zignol (all from the WHO Global TB Programme); Ajay Rangaraj and Elena Vovc (from the WHO Global HIV Programme); Soudeh Ehsani (WHO Regional Office for Europe); and Amos Fadare (WHO Country Office for Nigeria).
Guideline development group
Kobto Koura (Co-Chair), International Union Against Tuberculosis and Lung Disease, Paris,France; Jeremiah Chakaya Muhwa, Respiratory Society of Kenya, Nairobi, Kenya; Chamreun Sok Choub, Patients Advocate, Pnom Penh, Cambodia; Daniela Cirillo, San Raffaele Scientific Institute, Milan, Italy; Keertan Dheda, University of Cape Town, Cape Town, South Africa; Katherine Fielding, London School of Hygiene and Tropical Medicine, London, United Kingdom of Great Britain and Northern Ireland; Rumina Hasan, Aga Khan University, Karachi, Pakistan; Sirinapha Jittimanee, NTP Thailand Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand; Katharina Kranzer, London School of Hygiene and Tropical Medicine, London, United Kingdom of Great Britain and Northern Ireland; Andrei Mariandyshev, Northern State Medical University, Ministry of Health of Russia, Arkhangelsk, Russian Federation; Norbert Ndjeka, National TB Programme of South Africa, Pretoria, South Africa; Shaheed Vally Omar, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa; Hojoon Sohn, Seoul National University, Seoul, Republic of Korea, Thomas Shinnick, Consultant, Atlanta, USA; Sabira Tahseen, National Tuberculosis Control Programme, Ministry of National Health Services Regulations and Coordination, Government of Pakistan, Islamabad, Pakistan; Timothy Walker, University of Oxford, Ho Chi Minh City, Viet Nam; Xichao Ou, National Tuberculosis Control and Prevention Center, Chinese CDC; Beijing, China.
External review group
Martina Casenghi (Elizabeth Glaser Pediatric AIDS Foundation, Washington, USA), Jamilya Ismailova (National TB Program, Dushanbe, Tajikistan), Blessy Kumar (Global coalition of TB advocates, Delhi, India), Fernanda Dockhorn da Costa Johansen (National TB Program, Rio de Janeiro, Brazil), Petra de Haas (KNCV, The Hague, Netherlands), and Platon Eliseev (National
Center of Phtisiopulmonology, Moscow, Russian Federation).
Methodologist
Lawrence Mbuagbaw, McMaster University, Hamilton, Canada
Systematic review team
Review of diagnostic accuracy: Johanna Ahsberg (University of Southern Denmark, Odense, Denmark), Stephanie Bjerrum (University of Southern Denmark, Odense, Denmark), David Horne (University of Washington, Seattle, USA), Leeberk Raja Inbaraj (ICMR-National Institute for Research in Tuberculosis, Chennai, India), Nazir Ismail (Wits University, Johannesburg, South Africa), Alexander Kay (Baylor College of Medicine, Houston, USA), Mikashmi Kohli (FIND, Geneva Switzerland), Maia Madison (Baylor College of Medicine, Houston, USA), Laura Olbrich (LMU Klinikum, Munich, Germany), Katie Scandrett (University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland), Maunank Shah (John Hopkins University, Elkridge, USA), Yemisi Takwoingi (University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland)
Review of research into costs and cost effectiveness: Suvesh Shrestha and Alice Zwerling (University of Ottawa, Canada).
Review of and research into user perspectives, feasibility, and acceptability: Nora Engel (University of Maastricht, Maastricht, Netherlands) and Eleanor Ochodo (Kenya Medical Research Institute, Kisumu, Kenya).
Observers
Grania Bridgen Global Fund to Fight AIDS, TB and Malaria, Geneva, Switzlerland; Smiljka de Lussigny, Unitaid, Geneva, Switzerland; Anisa Ghadrshenas, Unitaid, Geneva, Switzerland; Brian Kaiser, Global Drug Facility, Stop TB Partnership, Geneva, Switzerland; Melanie Kitongo, Global Fund to Fight AIDS, TB and Malaria, Geneva, Switzerland; Adam Penn-Nicholson, FIND, Geneva Switzerland; Morten Ruhwald, FIND, Geneva, Switzerland.
Funding
Funding from the Gates Foundation is gratefully acknowledged. The views of the funding agencies have not influenced the development and content of these guidelines.