FeedbackAdvanced HIV disease: for adults, adolescents, and children aged 5 years or more, “advanced HIV disease” is defined as a CD4 cell count of less than 200 cells/mm³ or a WHO clinical stage 3 or 4 event at presentation for care. All children living with HIV aged under 5 years should be considered as having advanced disease at presentation.
Age groups: the following definitions for adults and children are used in these guidelines for the purpose of implementing recommendations (countries may have other definitions under their national regulations):
- an adult is a person aged 10 years and older;
- a child is a person aged under 10 years.
Grading of Recommendations Assessment, Development and Evaluation (GRADE): a system for rating quality of evidence and strength of recommendations; the GRADE approach is explicit, comprehensive, transparent and pragmatic, and is increasingly being adopted by organizations worldwide.
HIV serious illness: HIV serious illness is defined based on any of the following symptoms: respiratory rate of ≥ 30/minute, temperature ≥ 39 °C, heart rate ≥ 120/minute, or unable to walk unaided.
Inpatient health care setting: a health care facility where patients are admitted and assigned a bed while undergoing diagnosis and receiving treatment and care, for at least one overnight stay.
Outpatient health care setting: a health care facility where patients are undergoing diagnosis and receiving treatment and care but are not admitted for an overnight stay (e.g. an ambulatory clinic or a dispensary).